Includes bibliographical references and index.
|Statement||edited by D. Keppler.|
|The Physical Object|
|Pagination||x, 257 p.|
|Number of Pages||257|
*immediately available upon purchase as print book shipments may be delayed due to the COVID crisis. ebook access is temporary and does not include ownership of the ebook. Only valid for books with an ebook : Springer Netherlands. I Morphology of Liver Cell Necrosis.- 2 Morphologic Features of Hepatocellular Necrosis in Human Disease.- 3 Hydrolases and Cellular Death.- 4 Macromolecular Syntheses and the Maintenance of Liver Cell Integrity.- 5 Quantitative Aspects of Biochemical Mechanisms Leading to Cell Death.- 6 Pathogenesis of Hepatic Necrosis Caused by Amanitin. Pathogenesis and Mechanisms of Liver Cell Necrosis. Coronavirus: Find the latest articles and preprints Pathogenesis and Mechanisms of Liver Cell Necrosis. Scheuer PJ. Journal of Clinical Pathology, 01 Apr , 29(4): DOI: /jcpb PMCID. This is a PDF-only article. The first page of the PDF of this article appears above.
This regenerative capability of the liver is highly complex and involves, depending on the type and severity of the liver injury, cross talk between numerous resident hepatic cells and recruited bone marrow cells. Two main mechanisms account for the restoration of the liver mass after injury: proliferation of existing individual cell types. An abnormal wound healing process in response to a chronic liver injury is responsible for the pathogenesis of hepatic fibrosis and subsequent liver cirrhosis leading to . Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis which is aggravated by increased production of the proinflammatory cytokine tumor necrosis factor-alpha in the Kupffer cells. These are activated by induction of their CYP2E1 as well as by endotoxin. Progress in the understanding of the. Sandritter W., Riede U.N. () Morphology of liver cell necrosis. In: Keppler D. (eds) Pathogenesis and Mechanisms of Liver Cell Necrosis. Springer, Dordrecht.
Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by : P. J. Scheuer. Although apoptosis and oncotic necrosis have been considered distinct and independent phenomena, the two modes of cell death frequently coexist in liver pathology, which has led to spirited debates as to what mode of cell death is actually occurring in a given circumstance. 41 An alternative view is that necrosis and apoptosis are. The book is a collection of selected clinical and scientific topics divided into two volumes, each divided into two sections. The first volume treats the cellular, biochemical and immunological mechanisms underlying liver diseases; the second focuses on clinical liver disease pathophysiology and related diagnostics and therapeutic insights. APOPTOSIS AND NECROSIS Two Types of Cell Death in Alcoholic Liver Disease Amin A. Nanji, M.D., and Susanne Hiller-Sturmhöfel, Ph.D. Heavy alcohol consumption over long periods of time can result in severe liver damage, including death of liver cells (i.e., hepatocytes). Two mechanisms— apoptosis and necrosis—can contribute to hepatocyte death.